Lisinopril Conversion to ACE-Is and ARBs

	Approximate to Lisinopril 5mg	Equivalent to Lisinopril 10mg	Approximate to Lisinopril 20mg	Approximate to Lisinopril 40mg	Approximate to Lisinopril 80mg
Captopril	--	25mg BID	50mg BID	100mg BID	200mg BID
Enalapril	5mg	10mg	20mg	40mg	--
Ramipril	1.25mg	2.5mg	5mg	10mg	20mg
Benazepril	5mg	10mg	20mg	40mg	80mg
Fosinopril**	--	10mg	20mg	40mg	80mg
Moexipril	3.75mg	7.5mg	15mg	30mg	60mg
Perindopril	2mg	4mg	8mg	16mg	--
Trandolapril	0.5mg	1mg	2mg	4mg	4mg BID
Quinapril	5mg	10mg	20mg	40 mg	80mg
Candesartan	4mg	8mg	8-16mg	--	--
Valsartan	40mg	80mg	160mg	--	--
Losartan	25mg	50mg	100mg	--	--
Irbesartan	75mg	150mg	300mg	--	--
Olmesartan	5mg	10mg	20mg	--	--
Telmisartan	--	20mg	40mg	--	--

Lisinopril Conversion to ACE-Is and ARBs

 

 

*Approximate dosing was based off of ratios from known equivalent lisinopril doses

**If cough with lisinopril, Fosinopril (cough 2%-10%) may be used before switching to ARB

 

 

 

 

 

 

Kathryn Ley, our last pharmacy student, put this chart together.  Hopefully, it can serve as a good starting point. 

 

References:

Angiotensin converting enzyme (ACE) inhibitor antihypertensive dose comparison. Pharmacist's Letter/Prescriber's Letter 2009;25(8):250801.

Angiotensin receptor blocker (ARB) antihypertensive dose comparison. Pharmacist's Letter/Prescriber's Letter 2009;25(8):250801.

Diovan [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corp; 2011.

Lexi-Comp Online, Lexi-Drugs Online, Hudson, Ohio: Lexi-Comp, Inc.; 2011; September 12, 2011.