Tuesday, November 12, 2019

Pay $9600:Then you can breath , Icatibant,Firazyr

$9600 for 3 ml of medicine !

Hereditary angioedema (HAE) is a condition characterized by recurrent episodes of angioedema affecting the upper airway, bowel wall, or skin, which typically last two to four days. The angioedema of HAE is mediated by bradykinin and does not respond to epinephrine, antihistamines, or glucocorticoids. Instead, first-line therapies for HAE act by replacing the C1 inhibitor (C1INH) that is deficient or dysfunctional in this disease or by inhibiting the production or function of bradykinin.
However, the average $9600 wholesale cost of icatibant limits its use to patients experiencing airway compromise. "It's an incredibly expensive drug, but for the few patients with the most severe drug-induced angioedema, its use seems justified," he said.Nov 7, 2014

Cost of first-line therapies — All first-line therapies for acute attacks of HAE are costly. In the United States, the cost of one treatment with pdC1INH, ecallantide, or icatibant ranged from USD $5000 to 10,000 [81]. In European countries, the cost of one treatment with pdC1INH, rhC1INH, or icatibant is about 1500 to 2000 euros.

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