Thursday, November 07, 2019

Suboxone

Suboxone contains naloxone, an opioid antagonist, as well as buprenorphine. As a prescription, Suboxone is administered sublingually (under the tongue). Buprenorphine has good bioavailability when taken sublingually, but poor availability when injected. Naloxone is just the opposite, so its effects are not experienced when Suboxone is taken through the prescribed method, but when it is injected it blocks the opioid receptors and withdrawal symptoms are then triggered. This discourages the abuse of Suboxone by opioid addicted people. The drug can still be abused by non-addicted individuals with limited effect.

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