Wednesday, April 13, 2005

efficacies of centrally active drugs in erectile dysfunction

Apomorphine for erectile dysfunction

"Clinical bottom line
There is one randomised trial of sublingual apomorphine for the treatment of erectile dysfunction. Doses of 2-6 mg provided erections good enough for sexual intercourse in about 50% of men treated with apomorphine, compared with 32% with placebo. Six men would need to be treated with sublingual apomorphine for one to have successful erections who would not have had with placebo."
no wonder uprima is not another viagra !
any way my interest in apomorphine is froma different point of view .
apomorphine can produce yawning and penile erections even when amphetamine raised dopamine levels .
D3 reports are postulated to mediate the yawning response by extension
I hypothesise that orgasm is mediated by D3 receptors too.

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