Monday, July 03, 2017

Alexander the Gordian knot and transplantation

The Gordian Knot is a legend of Phrygian Gordium associated with Alexander the Great. It is often used as a metaphor for an intractable problem (disentangling an "impossible" knot) solved easily by loophole or "thinking outside the box" ("cutting the Gordian knot"):

So far Transplantation sciences have been Mired in trying to manipulate Human immune system.

But  Like Alexander I propose cutting the knot by creating DNA identical organs using the existing  technologies of "Human cloning" and "organ culture"

Step 1  Haploidentical organs from creation of expendable  human embryos which at the  age of 4 to 6 weeks gestation  will be  dissected for their  organs  which will be  f grown either in vitro  or in vivo in a surrogate , an immune suppressed  nonhuman primate or in  the  egg of an  emu or an Ostrich.
such organs will be used to transplant either a single large mature organ or multiple small immature organ tissues.
The technology for this exists in almost every district headquarters of India in every IVF center.
once we  master this technique  
 SCNT created embryos to create identical DNA carrying  organs for individual patients should be the  second  step
3rd would be the manipulation of the  antigens on the  created organs and creating of large Organ Factories  so that  a transplant recipient need not wait  8 to 9 months for an individual organ to be  grown for him and a readymade organ is available as and  when he/she needs it

No comments: