Saturday, April 16, 2005

Deadly flu virus

Apr 16, 2005, 13:45



"The World Health Organization says two samples of a deadly flu virus shipped to Mexico and Lebanon remain unaccounted for.

The virus, known as H2N2 , a strain of "Asian Flu," responsible for up to 4 million deaths worldwide in 1957 was shipped to 18 nations in the form of test kits, numbering close to 5000.

WHO influenza expert, Klaus Stohr, said the specimens were never received in Lebanon and Mexico, despite being on the distribution list.

The test kits containing the virus, distributed by Ohio's Meridian Bioscience Inc., were designed to test the ability of labs to identify virus strains."

the question no one seems to be asking is how come such a deadly viral specimen were stored by
"meridian Bioscience "?

what other deadly viruses are stored by different bio companies all over the world and specially in USA ?

what about ebola does CDC have any guidelines rules and precautions for such viral research ?

Wednesday, April 13, 2005

oxytocin and orgasm _yawning

Oxytocin receptor antagonists prevent apomorphine induced yawning .(orgasm )this suggests that dopamine (d3) receptor agonists induce yawning (erection/orgasm )by activating oxytocinergic neurons .

anxiety, drug abuse, sexual dysfunctions, eating disorders, or autism. treatment of theses disorders may be improved by elucidating all the neuropeptide actions of oxytocin .
the normal milk lettig reflex which is essentially breast/nipple stimulation causing oxytocin release and contraction of smooth muscle may be a reflex acting in female orgasm .
is this one of the rerasons for orgasms in breast stimulated women ?

efficacies of centrally active drugs in erectile dysfunction

Apomorphine for erectile dysfunction

"Clinical bottom line
There is one randomised trial of sublingual apomorphine for the treatment of erectile dysfunction. Doses of 2-6 mg provided erections good enough for sexual intercourse in about 50% of men treated with apomorphine, compared with 32% with placebo. Six men would need to be treated with sublingual apomorphine for one to have successful erections who would not have had with placebo."
no wonder uprima is not another viagra !
any way my interest in apomorphine is froma different point of view .
apomorphine can produce yawning and penile erections even when amphetamine raised dopamine levels .
D3 reports are postulated to mediate the yawning response by extension
I hypothesise that orgasm is mediated by D3 receptors too.

dreams some interesting facts

Congenitally blind have auditory dreams.
Acquired blind gradually lose their ability to dream visually.
Nightmares occur during REM sleep and during SWS with different characteristics:
SWS terrors are responsive to drugs that reduce SWS.

SWS terrors decrease with SWS decrease with age.

REM nightmares have storylines, SWS ones have image and poorer recall.

Dreams, yawning and orgasm

One of the most intence pleasurable sensations a man (or woman )can experience is the orgasm.
so much so in a science fiction classic the ability to record and replay emotions becomes common place an old engineer records an orgasm from a young couple then he starts using and reusing the tape to get the sensation over and over again so much so that he becomes like one of those rats with an electrode implanted in their pleasure center who keep on self stimulating ignoring all other activity .
he is so much in to this that he is committed by his wife to a mental asylum.
which neural stimulus produces this sensation (short of mastrubation which almost every boy and man knows )?
this is a question to be answered in detail .
there was a glimmer when it was reported patients who were taking the drug "clomiopramine " developed an orgasm when they yawned.

the paraventricular nucleus of hypothalamus is the trigger of yawning when stimulated by electrical impulses and chemicals such as histamine ( histamine the neglected neurotransmitter at a differenttime ).
so is the orgasmic center near the paraventricular nucleus of hypothalamus .
is there a way to produce orgasm on demand ?
is there a fatigue and nonreactive period for orgasm
why do mebn get orgasms more easily but are single but in women they are multiple ?
is this an inherent capbility or a learned reaction ?
I am r4ading up on all available material and may be soon will be able to report more stuff till then happy J*&king ;-)