Milestones in the history of diabetes

Ebers papyrus (Egipt, 1500BC)	Polyuric diseases
Charak and Sushrut (India,5th century BC)	Sweet urine diseases
“The Yellow Emperor’sCanon on the traditional Chinese Medicine” (China,4th century BC)	Sweet urine disease
Aretaeus (Cappadocia, 2nd century AD)	Polyuric state called “diabetes”
Avicenna (Arabia, 10thcentury, AD)	Sweet urine disease
Thomas Willis (England,1674)	Sweet urine disease
Matthew Dobson(England, 1776)	Hyperglycemia in urine and serum
John Rollo (England,1797)	Diabetes is called “diabetes mellitus” Design of the “animal diet”
Michel Chevreul (France,1815)	The sugar in the diabetic urine is glucose
Claude Bernard (France,1846–1848)	Glucose is stored in the liver as “glycogen” and released into the blood during fasting
Paul Langerhans (Germany, 1869)	Description of pancreatic islets
Etienne Lanceraux (France, 1880)	Classification of diabetes(“diabète maigre” and “diabète gras”)
Oskar Minkowski and Josef von Mering (Germany, 1890)	Link between diabetes and the pancreas. Pancreatectomy causes diabetes in dogs
Gustave Edouard Laguesse(France, 1893)	The “internal secretions” of the pancreas are produced by the “ islets of Langerhans ”
Jean de Meyer (Belgium,1909)	“Internal secretions” of the pancreas are called “insuline”
Frederick Banting, Charles Best, JJR Macleod and James Collip (Canada,1922)	Discovery of insulin