One 1.5-mL single-use applicator pen, which delivers 0.7 mL of solution, can treat approximately 7 typical lesions (~28 applications) and costs $130.5

CONCLUSION — Eskata, a 40% hydrogen peroxide topical solution, is the first FDA-approved drug for treatment of seborrheic keratoses. Administration of the drug may be tedious and usually requires at least two office visits. It has limited effectiveness and has not been shown to have fewer adverse cosmetic effects than standard procedures for removing these benign lesions.